COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF i...
COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF inhibitors
About this item
Full title
Author / Creator
Publisher
United States: Elsevier B.V
Journal title
Language
English
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Publication information
Publisher
United States: Elsevier B.V
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Scope and Contents
Contents
Keratoacanthomas (KAs) and cutaneous squamous cell carcinomas (cuSCCs) develop in 15–30% of patients with BRAFV600E metastatic melanoma treated with BRAF inhibitors (BRAFi). These lesions resemble mouse skin tumors induced by the two-stage DMBA/TPA skin carcinogenesis protocol; in this protocol BRAFi accelerates tumor induction. Since prior studies...
Alternative Titles
Full title
COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF inhibitors
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3943738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3943738
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1016/j.molonc.2013.11.005
