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SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3973117

SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

About this item

Full title

SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-04, Vol.124 (4), p.1636-1645

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The transcription factor SOX2 is an essential regulator of pluripotent stem cells and promotes development and maintenance of squamous epithelia. We previously reported that SOX2 is an oncogene and subject to highly recurrent genomic amplification in squamous cell carcinomas (SCCs). Here, we have further characterized the function of SOX2 in SCC. U...

Alternative Titles

Full title

SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3973117

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3973117

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI71545

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