Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calci...
Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Fragile X syndrome (FXS), the most common heritable form of mental retardation, is characterized by synaptic dysfunction. Synaptic transmission depends critically on presynaptic calcium entry via voltage-gated calcium (Ca
V
) channels. Here we show that the functional expression of neuronal N-type Ca
V
channels (Ca
V
2.2) is regul...
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Full title
Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3982139
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3982139
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4628