The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Precise control of organ size is crucial during animal development and regeneration. In
Drosophila
and mammals, studies over the past decade have uncovered a critical role for the Hippo tumour-suppressor pathway in the regulation of organ size. Dysregulation of this pathway leads to massive overgrowth of tissue. The Hippo signalling pathway i...
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Full title
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3987945
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3987945
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2303