ASK1 promotes the contact hypersensitivity response through IL-17 production
ASK1 promotes the contact hypersensitivity response through IL-17 production
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Contact hypersensitivity (CHS) is a form of delayed-type hypersensitivity triggered by the response to reactive haptens (sensitization) and subsequent challenge (elicitation). Here, we show that ASK1 promotes CHS and that suppression of ASK1 during the elicitation phase is sufficient to attenuate CHS. ASK1 knockout (KO) mice exhibited impaired 2,4-...
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Full title
ASK1 promotes the contact hypersensitivity response through IL-17 production
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3988482
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3988482
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep04714
