Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during r...
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency
About this item
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Author / Creator
Wang, Tao , Wu, Hao , Li, Yujing , Szulwach, Keith E. , Lin, Li , Li, Xuekun , Chen, I-Ping , Goldlust, Ian S. , Chamberlain, Stormy J. , Dodd, Ann , Gong, He , Ananiev, Gene , Han, Ji Woong , Yoon, Young-sup , Katharine Rudd, M. , Yu, Miao , Song, Chun-Xiao , He, Chuan , Chang, Qiang , Warren, Stephen T. and Jin, Peng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Mammalian somatic cells can be directly reprogrammed into induced pluripotent stem cells (iPSCs) by introducing defined sets of transcription factors. Somatic cell reprogramming involves epigenomic reconfiguration, conferring iPSCs with characteristics similar to embryonic stem cells (ESCs). Human ESCs (hESCs) contain 5-hydroxymethylcytosine (5hmC)...
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Full title
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3998089
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3998089
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2748
