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Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma

Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001532

Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma

About this item

Full title

Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-05, Vol.124 (5), p.1956-1965

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Administration of glucocorticoids induces ocular hypertension in some patients. If untreated, these patients can develop a secondary glaucoma that resembles primary open-angle glaucoma (POAG). The underlying pathology of glucocorticoid-induced glaucoma is not fully understood, due in part to lack of an appropriate animal model. Here, we developed a...

Alternative Titles

Full title

Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001532

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001532

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI69774

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