A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque...
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation
About this item
Full title
Author / Creator
Duivenvoorden, Raphaël , Tang, Jun , Cormode, David P. , Mieszawska, Aneta J. , Izquierdo-Garcia, David , Ozcan, Canturk , Otten, Maarten J. , Zaidi, Neeha , Lobatto, Mark E. , van Rijs, Sarian M. , Priem, Bram , Kuan, Emma L. , Martel, Catherine , Hewing, Bernd , Sager, Hendrik , Nahrendorf, Matthias , Randolph, Gwendalyn J. , Stroes, Erik S. G. , Fuster, Valentin , Fisher, Edward A. , Fayad, Zahi A. and Mulder, Willem J. M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Inflammation is a key feature of atherosclerosis and a target for therapy. Statins have potent anti-inflammatory properties but these cannot be fully exploited with oral statin therapy due to low systemic bioavailability. Here we present an injectable reconstituted high-density lipoprotein (rHDL) nanoparticle carrier vehicle that delivers statins t...
Alternative Titles
Full title
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation
Authors, Artists and Contributors
Author / Creator
Tang, Jun
Cormode, David P.
Mieszawska, Aneta J.
Izquierdo-Garcia, David
Ozcan, Canturk
Otten, Maarten J.
Zaidi, Neeha
Lobatto, Mark E.
van Rijs, Sarian M.
Priem, Bram
Kuan, Emma L.
Martel, Catherine
Hewing, Bernd
Sager, Hendrik
Nahrendorf, Matthias
Randolph, Gwendalyn J.
Stroes, Erik S. G.
Fuster, Valentin
Fisher, Edward A.
Fayad, Zahi A.
Mulder, Willem J. M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001802
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001802
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4065
