Pharmacokinetics of CTLA4Ig fusion protein in healthy volunteers and patients with rheumatoid arthri...
Pharmacokinetics of CTLA4Ig fusion protein in healthy volunteers and patients with rheumatoid arthritis
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Author / Creator
Ma, Ying , Lin, Bi-rong , Lin, Bei , Hou, Sheng , Qian, Wei-zhu , Li, Jing , Tan, Min , Ma, Jian , Li, Bo-hua , Wang, Hao , Wen, Ai-dong and Guo, Ya-jun
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Aim: To evaluate single-dose and multiple-dose pharmacokinetics of cytotoxic T-lymphocyte-associated antigen 4 fusion protein (CTLA4Ig) in healthy volunteers and patients with rheumatoid arthritis (RA).
Methods: The clinical trials included two phase I open studies: study 1 was an open-label dose-escalation study in 27 healthy volunteers and stu...
Alternative Titles
Full title
Pharmacokinetics of CTLA4Ig fusion protein in healthy volunteers and patients with rheumatoid arthritis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4002403
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4002403
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/aps.2009.13