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Macrophage colony stimulating factor induces macrophage proliferation and survival through a pathway...

Macrophage colony stimulating factor induces macrophage proliferation and survival through a pathway...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4004764

Macrophage colony stimulating factor induces macrophage proliferation and survival through a pathway involving DAP12 and β-catenin

About this item

Full title

Macrophage colony stimulating factor induces macrophage proliferation and survival through a pathway involving DAP12 and β-catenin

Journal title

Nature immunology, 2009-06, Vol.10 (7), p.734-743

Language

English

Formats

More information

Scope and Contents

Contents

Macrophage colony stimulating factor (MCSF) influences proliferation and survival of mononuclear phagocytes through the CSF-1 receptor. The DAP12 adaptor protein, which transduces signals emanating from various myeloid receptors, is critical for mononuclear phagocyte function. DAP12-mutant mice and humans show defects in osteoclasts and microglia a...

Alternative Titles

Full title

Macrophage colony stimulating factor induces macrophage proliferation and survival through a pathway involving DAP12 and β-catenin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4004764

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4004764

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.1744

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