WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer
WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Inflammatory breast cancer (IBC) is the most lethal form of locally advanced breast cancer. We found concordant and consistent alterations of two genes in 90% of IBC tumors when compared to stage matched, non-IBC tumors: overexpression of RhoC GTPase and loss of WISP3. Further work revealed that RhoC is a transforming oncogene for HME cells. Despit...
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Full title
WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_400654
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_400654
Other Identifiers
ISSN
1465-542X,1465-5411
E-ISSN
1465-542X
DOI
10.1186/bcr755
