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WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer

WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_400654

WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer

About this item

Full title

WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer

Publisher

England: BioMed Central Ltd

Journal title

Breast cancer research : BCR, 2004-01, Vol.6 (1), p.R110-R115, Article R110

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Inflammatory breast cancer (IBC) is the most lethal form of locally advanced breast cancer. We found concordant and consistent alterations of two genes in 90% of IBC tumors when compared to stage matched, non-IBC tumors: overexpression of RhoC GTPase and loss of WISP3. Further work revealed that RhoC is a transforming oncogene for HME cells. Despit...

Alternative Titles

Full title

WISP3 and RhoC guanosine triphosphatase cooperate in the development of inflammatory breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_400654

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_400654

Other Identifiers

ISSN

1465-542X,1465-5411

E-ISSN

1465-542X

DOI

10.1186/bcr755

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