Retinoid X receptor gamma signaling accelerates CNS remyelination
Retinoid X receptor gamma signaling accelerates CNS remyelination
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The authors report a transcriptional profile of the discrete stages of spontaneous remyelination following toxin-induced focal demyelination in rats. They find an enrichment of retinoid X receptor (RXR) signaling pathways over the course of remyelination and show that RXR activation stimulates oligodendrocyte differentiation to enhance remyelinatio...
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Full title
Retinoid X receptor gamma signaling accelerates CNS remyelination
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4013508
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4013508
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2702