Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Oncogene-induced reactive oxygen species (ROS) have been proposed to be signaling molecules that mediate proliferative cues. However, ROS may also cause DNA damage and proliferative arrest. How these apparently opposite roles can be reconciled, especially in the context of oncogene-induced cellular senescence, which is associated both with aberrant...
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Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4013514
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4013514
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2014.16