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Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4013514

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

About this item

Full title

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2014-06, Vol.21 (6), p.998-1012

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Oncogene-induced reactive oxygen species (ROS) have been proposed to be signaling molecules that mediate proliferative cues. However, ROS may also cause DNA damage and proliferative arrest. How these apparently opposite roles can be reconciled, especially in the context of oncogene-induced cellular senescence, which is associated both with aberrant...

Alternative Titles

Full title

Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4013514

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4013514

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/cdd.2014.16

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