tmc-1 encodes a sodium-sensitive channel required for salt chemosensation in C. elegans
tmc-1 encodes a sodium-sensitive channel required for salt chemosensation in C. elegans
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The membrane protein TMC-1 is required for salt avoidance behaviour in
C. elegans
, functions as an ion channel directly activated by NaCl
in vitro
and is a candidate salt chemosensor; the human homologue of TMC-1 is linked to deafness and may be the cochlear hair-cell mechanotransduction channel.
TMC-1 protein makes sense of salt
Alternative Titles
Full title
tmc-1 encodes a sodium-sensitive channel required for salt chemosensation in C. elegans
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4021456
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4021456
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11845
