Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
About this item
Full title
Author / Creator
Behjati, Sam , Tarpey, Patrick S , Sheldon, Helen , Martincorena, Inigo , Van Loo, Peter , Gundem, Gunes , Wedge, David C , Ramakrishna, Manasa , Cooke, Susanna L , Pillay, Nischalan , Vollan, Hans Kristian M , Papaemmanuil, Elli , Koss, Hans , Bunney, Tom D , Hardy, Claire , Joseph, Olivia R , Martin, Sancha , Mudie, Laura , Butler, Adam , Teague, Jon W , Patil, Meena , Steers, Graham , Cao, Yu , Gumbs, Curtis , Ingram, Davis , Lazar, Alexander J , Little, Latasha , Mahadeshwar, Harshad , Protopopov, Alexei , Al Sannaa, Ghadah A , Seth, Sahil , Song, Xingzhi , Tang, Jiabin , Zhang, Jianhua , Ravi, Vinod , Torres, Keila E , Khatri, Bhavisha , Halai, Dina , Roxanis, Ioannis , Baumhoer, Daniel , Tirabosco, Roberto , Amary, M Fernanda , Boshoff, Chris , McDermott, Ultan , Katan, Matilda , Stratton, Michael R , Futreal, P Andrew , Flanagan, Adrienne M , Harris, Adrian and Campbell, Peter J
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Peter Campbell and colleagues identify
PLCG1
and
PTPRB
as new driver genes for angiosarcoma through whole-exome sequencing of tumor samples. They find somatic
PTPRB
mutations in 10 of 39 cases and
PLCG1
mutations in 3 of 34 cases, along with mutations in known cancer-related genes.
Angiosarcoma is an aggressive malignancy...
Alternative Titles
Full title
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Authors, Artists and Contributors
Author / Creator
Tarpey, Patrick S
Sheldon, Helen
Martincorena, Inigo
Van Loo, Peter
Gundem, Gunes
Wedge, David C
Ramakrishna, Manasa
Cooke, Susanna L
Pillay, Nischalan
Vollan, Hans Kristian M
Papaemmanuil, Elli
Koss, Hans
Bunney, Tom D
Hardy, Claire
Joseph, Olivia R
Martin, Sancha
Mudie, Laura
Butler, Adam
Teague, Jon W
Patil, Meena
Steers, Graham
Cao, Yu
Gumbs, Curtis
Ingram, Davis
Lazar, Alexander J
Little, Latasha
Mahadeshwar, Harshad
Protopopov, Alexei
Al Sannaa, Ghadah A
Seth, Sahil
Song, Xingzhi
Tang, Jiabin
Zhang, Jianhua
Ravi, Vinod
Torres, Keila E
Khatri, Bhavisha
Halai, Dina
Roxanis, Ioannis
Baumhoer, Daniel
Tirabosco, Roberto
Amary, M Fernanda
Boshoff, Chris
McDermott, Ultan
Katan, Matilda
Stratton, Michael R
Futreal, P Andrew
Flanagan, Adrienne M
Harris, Adrian
Campbell, Peter J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4032873
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4032873
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2921
