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Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s dis...

Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s dis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4034750

Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials

About this item

Full title

Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2014-06, Vol.127 (6), p.861-879

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Immunotherapeutic approaches are currently in the spotlight for their potential as disease-modifying treatments for neurodegenerative disorders. The discovery that α-synuclein (α-syn) can transmit from cell to cell in a prion-like fashion suggests that immunization might be a viable option for the treatment of synucleinopathies. This possibility ha...

Alternative Titles

Full title

Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4034750

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4034750

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-014-1256-4

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