Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s dis...
Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Immunotherapeutic approaches are currently in the spotlight for their potential as disease-modifying treatments for neurodegenerative disorders. The discovery that α-synuclein (α-syn) can transmit from cell to cell in a prion-like fashion suggests that immunization might be a viable option for the treatment of synucleinopathies. This possibility ha...
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Full title
Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4034750
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4034750
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ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-014-1256-4