Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat
Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Chemotherapy with doxorubicin is limited by cardiotoxicity. Free radical generation and mitochondrial dysfunction are thought to contribute to doxorubicin-induced cardiac failure. In this study we wanted to investigate if opening of mitochondrial KATP-channels by diazoxide is protective against doxorubicin cardiotoxicity, and if 5-hydroxydecanoate...
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Full title
Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4045949
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4045949
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ISSN
2050-6511
E-ISSN
2050-6511
DOI
10.1186/2050-6511-15-28