Log in to save to my catalogue

Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat

Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4045949

Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat

About this item

Full title

Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat

Publisher

England: BioMed Central Ltd

Journal title

BMC pharmacology & toxicology, 2014-05, Vol.15 (1), p.28-28, Article 28

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Chemotherapy with doxorubicin is limited by cardiotoxicity. Free radical generation and mitochondrial dysfunction are thought to contribute to doxorubicin-induced cardiac failure. In this study we wanted to investigate if opening of mitochondrial KATP-channels by diazoxide is protective against doxorubicin cardiotoxicity, and if 5-hydroxydecanoate...

Alternative Titles

Full title

Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4045949

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4045949

Other Identifiers

ISSN

2050-6511

E-ISSN

2050-6511

DOI

10.1186/2050-6511-15-28

How to access this item