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Origin and function of myofibroblasts in kidney fibrosis

Origin and function of myofibroblasts in kidney fibrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4067127

Origin and function of myofibroblasts in kidney fibrosis

About this item

Full title

Origin and function of myofibroblasts in kidney fibrosis

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2013-08, Vol.19 (8), p.1047-1053

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Myofibroblasts are associated with organ fibrosis, but their origin and functional role remain unknown. Using multiple genetically engineered mice, the authors found that in the kidney, myofibroblasts arise from multiple sources—resident fibroblasts, bone marrow, endothelial cells and epithelial cells. Targeting these different populations may ther...

Alternative Titles

Full title

Origin and function of myofibroblasts in kidney fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4067127

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4067127

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3218

How to access this item