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Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4076119

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

About this item

Full title

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

Publisher

London: Nature Publishing Group UK

Journal title

Nature, 2007-06, Vol.447 (7147), p.959-965

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient mice have shown that this lipid chaperone has a significant role in several aspects of metabolic syndrome, including type 2 diabetes and atherosclerosis. Here we demonstrate that...

Alternative Titles

Full title

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4076119

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4076119

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687,1476-4679

DOI

10.1038/nature05844

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