A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?
A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The inflammasome is a protein complex that comprises an intracellular sensor (typically a Nod-like receptor), the precursor procaspase-1 and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, interleukin 1β (IL-1β) and IL-18. Although initially the inflammasome was described as a comp...
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A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4090390
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4090390
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2228