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A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4090390

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

About this item

Full title

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2012-04, Vol.13 (4), p.352-357

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The inflammasome is a protein complex that comprises an intracellular sensor (typically a Nod-like receptor), the precursor procaspase-1 and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, interleukin 1β (IL-1β) and IL-18. Although initially the inflammasome was described as a comp...

Alternative Titles

Full title

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4090390

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4090390

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.2228

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