Structural and molecular interrogation of intact biological systems
Structural and molecular interrogation of intact biological systems
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Author / Creator
Chung, Kwanghun , Wallace, Jenelle , Kim, Sung-Yon , Kalyanasundaram, Sandhiya , Andalman, Aaron S. , Davidson, Thomas J. , Mirzabekov, Julie J. , Zalocusky, Kelly A. , Mattis, Joanna , Denisin, Aleksandra K. , Pak, Sally , Bernstein, Hannah , Ramakrishnan, Charu , Grosenick, Logan , Gradinaru, Viviana and Deisseroth, Karl
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Obtaining high-resolution information from a complex system, while maintaining the global perspective needed to understand system function, represents a key challenge in biology. Here we address this challenge with a method (termed CLARITY) for the transformation of intact tissue into a nanoporous hydrogel-hybridized form (crosslinked to a three-di...
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Full title
Structural and molecular interrogation of intact biological systems
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4092167
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4092167
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12107
