Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus
Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
This study shows that neural progenitor cells in the adult hippocampus of mice receive immature GABAergic synaptic inputs from parvalbumin (PV)-expressing interneurons, and uses optogenetic stimulation to demonstrate local PV interneuron activation via GABA signaling promotes survival and maturation of newborn neurons.
Using immunohistology, ele...
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Full title
Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096812
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096812
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3572