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Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus

Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096812

Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus

About this item

Full title

Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2013-12, Vol.16 (12), p.1728-1730

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

This study shows that neural progenitor cells in the adult hippocampus of mice receive immature GABAergic synaptic inputs from parvalbumin (PV)-expressing interneurons, and uses optogenetic stimulation to demonstrate local PV interneuron activation via GABA signaling promotes survival and maturation of newborn neurons.
Using immunohistology, ele...

Alternative Titles

Full title

Parvalbumin interneurons mediate neuronal circuitry–neurogenesis coupling in the adult hippocampus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096812

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096812

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.3572

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