Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhi...
Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhibit enhanced phagocytosis and immunogenicity
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Publisher
Kidlington: Elsevier Ltd
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Language
English
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Publisher
Kidlington: Elsevier Ltd
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Scope and Contents
Contents
Highlights • Calcium phosphate slows antigen release from protein coated microcrystals. • Specific IgG titres are enhanced for a number of model antigens. • Immunogenicity does not correlate with rate of antigen release from depot. • Th1-biased immunity is higher than with alum adjuvant. • Phagocytosis is promoted by calcium phosphate modification.
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Full title
Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhibit enhanced phagocytosis and immunogenicity
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4101235
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4101235
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2013.09.061