Log in to save to my catalogue

Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhi...

Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4101235

Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhibit enhanced phagocytosis and immunogenicity

About this item

Full title

Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhibit enhanced phagocytosis and immunogenicity

Publisher

Kidlington: Elsevier Ltd

Journal title

Vaccine, 2014-07, Vol.32 (33), p.4234-4242

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights • Calcium phosphate slows antigen release from protein coated microcrystals. • Specific IgG titres are enhanced for a number of model antigens. • Immunogenicity does not correlate with rate of antigen release from depot. • Th1-biased immunity is higher than with alum adjuvant. • Phagocytosis is promoted by calcium phosphate modification.

Alternative Titles

Full title

Protein coated microcrystals formulated with model antigens and modified with calcium phosphate exhibit enhanced phagocytosis and immunogenicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4101235

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4101235

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2013.09.061

How to access this item