Localized interleukin‐12 delivery for immunotherapy of solid tumours
Localized interleukin‐12 delivery for immunotherapy of solid tumours
About this item
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Author / Creator
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
England: John Wiley & Sons, Inc
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More information
Scope and Contents
Contents
Interleukin (IL)‐12 is the key cytokine in the initiation of a Th1 response and has shown promise as an anti‐cancer agent; however, clinical trials involving IL‐12 have been unsuccessful due to toxic side‐effects. To address this issue, lentiviral vectors were used to transduce tumour cell lines that were injected as an autologous tumour cell vacci...
Alternative Titles
Full title
Localized interleukin‐12 delivery for immunotherapy of solid tumours
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4117559
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4117559
Other Identifiers
ISSN
1582-1838
E-ISSN
1582-4934
DOI
10.1111/jcmm.12121