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Localized interleukin‐12 delivery for immunotherapy of solid tumours

Localized interleukin‐12 delivery for immunotherapy of solid tumours

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4117559

Localized interleukin‐12 delivery for immunotherapy of solid tumours

About this item

Full title

Localized interleukin‐12 delivery for immunotherapy of solid tumours

Publisher

England: John Wiley & Sons, Inc

Journal title

Journal of cellular and molecular medicine, 2013-11, Vol.17 (11), p.1465-1474

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Interleukin (IL)‐12 is the key cytokine in the initiation of a Th1 response and has shown promise as an anti‐cancer agent; however, clinical trials involving IL‐12 have been unsuccessful due to toxic side‐effects. To address this issue, lentiviral vectors were used to transduce tumour cell lines that were injected as an autologous tumour cell vacci...

Alternative Titles

Full title

Localized interleukin‐12 delivery for immunotherapy of solid tumours

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4117559

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4117559

Other Identifiers

ISSN

1582-1838

E-ISSN

1582-4934

DOI

10.1111/jcmm.12121

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