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A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123303

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression

About this item

Full title

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression

Publisher

London: Nature Publishing Group UK

Journal title

Cell research, 2014-08, Vol.24 (8), p.994-1008

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Thyroid transcription factor-1 (TTF-1, also known as NKX2-1) is a tissue-specific transcription factor in lung epithelial cells. Although TTF-1 inhibits the epithelial-to-mesenchymal transition induced by transforming growth factor-β (TGF-β) in lung adenocarcinoma cells, the mechanism through which TTF-1 inhibits the functions of TGF-β is unknown....

Alternative Titles

Full title

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123303

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123303

Other Identifiers

ISSN

1001-0602

E-ISSN

1748-7838

DOI

10.1038/cr.2014.97

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