A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression
A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Thyroid transcription factor-1 (TTF-1, also known as NKX2-1) is a tissue-specific transcription factor in lung epithelial cells. Although TTF-1 inhibits the epithelial-to-mesenchymal transition induced by transforming growth factor-β (TGF-β) in lung adenocarcinoma cells, the mechanism through which TTF-1 inhibits the functions of TGF-β is unknown....
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Full title
A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123303
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123303
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2014.97