Advances in targeting cyclic nucleotide phosphodiesterases
Advances in targeting cyclic nucleotide phosphodiesterases
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
The nucleotides cAMP and cGMP both regulate myriad effects in virtually all animal cells. These actions are coordinated through protein kinase A (PKA), PKG, exchange factor directly activated by cAMP1 (EPAC1), EPAC2 and cyclic nucleotide-gated ion channels.
Intracellular levels of cAMP and cGMP are controlled through their synthesi...
Alternative Titles
Full title
Advances in targeting cyclic nucleotide phosphodiesterases
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4155750
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4155750
Other Identifiers
ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd4228
