Mdmx promotes genomic instability independent of p53 and Mdm2
Mdmx promotes genomic instability independent of p53 and Mdm2
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
The oncogene Mdmx is overexpressed in many human malignancies, and together with Mdm2, negatively regulates the p53 tumor suppressor. However, a p53-independent function of Mdmx that impacts genome stability has been described, but this function is not well understood. In the present study, we determined that of the 13 different cancer types evalua...
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Full title
Mdmx promotes genomic instability independent of p53 and Mdm2
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4160436
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4160436
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2014.27
