Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The HEK293 human cell lineage is widely used in cell biology and biotechnology. Here we use whole-genome resequencing of six 293 cell lines to study the dynamics of this aneuploid genome in response to the manipulations used to generate common 293 cell derivatives, such as transformation and stable clone generation (293T); suspension growth adaptat...
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Full title
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4166678
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4166678
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms5767