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Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4166678

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

About this item

Full title

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2014-09, Vol.5 (1), p.4767-4767, Article 4767

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The HEK293 human cell lineage is widely used in cell biology and biotechnology. Here we use whole-genome resequencing of six 293 cell lines to study the dynamics of this aneuploid genome in response to the manipulations used to generate common 293 cell derivatives, such as transformation and stable clone generation (293T); suspension growth adaptat...

Alternative Titles

Full title

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4166678

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4166678

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms5767

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