PTEN is a protein tyrosine phosphatase for IRS1
PTEN is a protein tyrosine phosphatase for IRS1
About this item
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Tumor suppressor PTEN negatively regulates PI3K-AKT signaling by dephosphorylating PIP3. PTEN can also dephosphorylate peptide substrates
in vitro
, but the physiological relevance of this activity was unclear. Jiang and colleagues show that PTEN is a protein tyrosine phosphatase that selectively dephosphorylates insulin receptor substrate-1...
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Full title
PTEN is a protein tyrosine phosphatase for IRS1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4167033
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4167033
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2828
