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Laquinimod reduces neuroaxonal injury through inhibiting microglial activation

Laquinimod reduces neuroaxonal injury through inhibiting microglial activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4184669

Laquinimod reduces neuroaxonal injury through inhibiting microglial activation

About this item

Full title

Laquinimod reduces neuroaxonal injury through inhibiting microglial activation

Publisher

United States: John Wiley & Sons, Inc

Journal title

Annals of clinical and translational neurology, 2014-06, Vol.1 (6), p.409-422

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Objective
Laquinimod is an emerging oral medication for multiple sclerosis (MS) that reduces brain atrophy and progression of disability in two Phase III clinical trials. The mechanism of these effects is unclear. Persistent activation of microglia occurs in MS and contributes to injury. Thus, we investigated whether laquinimod alters properties...

Alternative Titles

Full title

Laquinimod reduces neuroaxonal injury through inhibiting microglial activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4184669

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4184669

Other Identifiers

ISSN

2328-9503

E-ISSN

2328-9503

DOI

10.1002/acn3.67

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