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The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4185421

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

About this item

Full title

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2014-05, Vol.344 (6184), p.645-648

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Tissue-resident macrophages are heterogeneous as a consequence of anatomical niche–specific functions. Many populations self-renew independently of bone marrow in the adult, but the molecular mechanisms of this are poorly understood. We determined a transcriptional profile for the major self-renewing population of peritoneal macrophages in mice. Th...

Alternative Titles

Full title

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4185421

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4185421

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1251414

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