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Warped linear mixed models for the genetic analysis of transformed phenotypes

Warped linear mixed models for the genetic analysis of transformed phenotypes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4199105

Warped linear mixed models for the genetic analysis of transformed phenotypes

About this item

Full title

Warped linear mixed models for the genetic analysis of transformed phenotypes

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2014-09, Vol.5 (1), p.4890-4890, Article 4890

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Linear mixed models (LMMs) are a powerful and established tool for studying genotype–phenotype relationships. A limitation of the LMM is that the model assumes Gaussian distributed residuals, a requirement that rarely holds in practice. Violations of this assumption can lead to false conclusions and loss in power. To mitigate this problem, it is co...

Alternative Titles

Full title

Warped linear mixed models for the genetic analysis of transformed phenotypes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4199105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4199105

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms5890

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