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ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4219162

ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

About this item

Full title

ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2014-11, Vol.4 (1), p.6899, Article 6899

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Epigenetic silencing through promoter hypermethylation is an important hallmark for the inactivation of tumor-related genes in carcinogenesis. Here we identified the
ATP-binding cassette sub-family B member 4 (ABCB4)
as a novel epigenetically silenced target gene. We investigated the epigenetic regulation of
ABCB4
in 26 human lung, brea...

Alternative Titles

Full title

ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4219162

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4219162

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep06899

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