Genome sequencing of normal cells reveals developmental lineages and mutational processes
Genome sequencing of normal cells reveals developmental lineages and mutational processes
About this item
Full title
Author / Creator
Behjati, Sam , Huch, Meritxell , van Boxtel, Ruben , Karthaus, Wouter , Wedge, David C. , Tamuri, Asif U. , Martincorena, Iñigo , Petljak, Mia , Alexandrov, Ludmil B. , Gundem, Gunes , Tarpey, Patrick S. , Roerink, Sophie , Blokker, Joyce , Maddison, Mark , Mudie, Laura , Robinson, Ben , Nik-Zainal, Serena , Campbell, Peter , Goldman, Nick , van de Wetering, Marc , Cuppen, Edwin , Clevers, Hans and Stratton, Michael R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
On the basis of whole-genome sequences of clonal lines derived from normal mouse tissues, variation in mutational patterns and load across different tissues are described and early embryonic cell divisions are reconstructed.
Cell lineage trees
By whole-genome sequencing of clonal lines derived from multiple tissues of healthy mice, Michael St...
Alternative Titles
Full title
Genome sequencing of normal cells reveals developmental lineages and mutational processes
Authors, Artists and Contributors
Author / Creator
Huch, Meritxell
van Boxtel, Ruben
Karthaus, Wouter
Wedge, David C.
Tamuri, Asif U.
Martincorena, Iñigo
Petljak, Mia
Alexandrov, Ludmil B.
Gundem, Gunes
Tarpey, Patrick S.
Roerink, Sophie
Blokker, Joyce
Maddison, Mark
Mudie, Laura
Robinson, Ben
Nik-Zainal, Serena
Campbell, Peter
Goldman, Nick
van de Wetering, Marc
Cuppen, Edwin
Clevers, Hans
Stratton, Michael R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4227286
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4227286
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13448
