Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Trans...
Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease
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Basingstoke: Nature Publishing Group
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Language
English
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Basingstoke: Nature Publishing Group
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Contents
Triggering receptor expressed on myeloid cells 2 (TREM2) gene is a recently identified susceptibility gene for Alzheimer's disease (AD), as its low-frequency variants increase the risk of this disease with an odds ratio similar to that of an APOE ɛ4 allele. To date, the expression and biologic functions of TREM2 under AD context remain largely unkn...
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Full title
Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4229581
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4229581
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ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/npp.2014.164
