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Autophagy is essential for effector CD8+ T cell survival and memory formation

Autophagy is essential for effector CD8+ T cell survival and memory formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4232981

Autophagy is essential for effector CD8+ T cell survival and memory formation

About this item

Full title

Autophagy is essential for effector CD8+ T cell survival and memory formation

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2014-12, Vol.15 (12), p.1152-1161

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Autophagy has essential roles in cellular energy mobilization and homeostasis, but its role in T cell memory formation is remains poorly understood. Ahmed and colleagues demonstrate that autophagy is critical for the survival of cytotoxic memory cells.
The importance of autophagy in the generation of memory CD8
+
T cells
in vivo
is n...

Alternative Titles

Full title

Autophagy is essential for effector CD8+ T cell survival and memory formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4232981

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4232981

Other Identifiers

ISSN

1529-2908,1529-2916

E-ISSN

1529-2916

DOI

10.1038/ni.3025

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