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How the ribosome hands the A-site tRNA to the P site during EF-G–catalyzed translocation

How the ribosome hands the A-site tRNA to the P site during EF-G–catalyzed translocation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4242719

How the ribosome hands the A-site tRNA to the P site during EF-G–catalyzed translocation

About this item

Full title

How the ribosome hands the A-site tRNA to the P site during EF-G–catalyzed translocation

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2014-09, Vol.345 (6201), p.1188-1191

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Coupled translocation of messenger RNA and transfer RNA (tRNA) through the ribosome, a process catalyzed by elongation factor EF-G, is a crucial step in protein synthesis. The crystal structure of a bacterial translocation complex describes the binding states of two tRNAs trapped in mid-translocation. The deacylated P-site tRNA has moved into a par...

Alternative Titles

Full title

How the ribosome hands the A-site tRNA to the P site during EF-G–catalyzed translocation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4242719

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4242719

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1255030

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