Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Scope and Contents
Contents
Following biosynthesis, both GLUT1 and VSV‐G proteins appear rapidly (2–3 h) at the plasma membrane, whereas GLUT4 is retained in intracellular membrane compartments and does not display any significant insulin responsiveness until 6–9 h. Surprisingly, the acquisition of insulin responsiveness did not require plasma membrane endocytosis, as express...
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Full title
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_424358
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_424358
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/sj.emboj.7600159
