Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics
Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics
About this item
Full title
Author / Creator
Inversen, Lars , Tu, Hsiung-Lin , Lin, Wan-Chen , Christensen, Sune M. , Abel, Steven M. , Iwig, Jeff , Wu, Hung-Jen , Gureasko, Jodi , Rhodes, Christopher , Petit, Rebecca S. , Hansen, Scott D. , Thill, Peter , Yu, Cheng-Han , Stamou, Dimitrios , Chakraborty, Arup K. , Kuriyan, John and Groves, Jay T.
Publisher
Washington: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington: American Association for the Advancement of Science
Subjects
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Scope and Contents
Contents
Activation of the small guanosine triphosphatase H-Ras by the exchange
factor Son of Sevenless (SOS) is an important hub for signal
transduction. Multiple layers of regulation, through protein and
membrane interactions, govern activity of SOS. We characterized the
specific activity of individual SOS molecules catalyzing nucleotide
ex...
Alternative Titles
Full title
Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255705
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4255705
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1250373
