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IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4299647

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo

About this item

Full title

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory and critical care medicine, 2014-12, Vol.190 (12), p.1373-1382

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

Rhinoviruses are the major cause of asthma exacerbations; however, its underlying mechanisms are poorly understood. We hypothesized that the epithelial cell-derived cytokine IL-33 plays a central role in exacerbation pathogenesis through augmentation of type 2 inflammation.
To assess whether rhinovirus induces a type 2 inflammatory response in a...

Alternative Titles

Full title

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4299647

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4299647

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.201406-1039OC

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