Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia
Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Selective elimination of synaptic connections is a common phenomenon which occurs during both developmental and pathological conditions. Glial cells have a central role in the pruning of synapses by specifically engulfing the degenerating neurites of inappropriate connections, but its regulatory mechanisms have been largely unknown. To identify med...
Alternative Titles
Full title
Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia
Authors, Artists and Contributors
Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4303875
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4303875
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep07989
