Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming...
Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
DNA methylomes are extensively reprogrammed during mouse pre-implantation and early germ cell development. The main feature of this reprogramming is a genome-wide decrease in 5-methylcytosine (5mC). Standard high-resolution single-stranded bisulfite sequencing techniques do not allow discrimination of the underlying passive (replication-dependent)...
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Full title
Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4304184
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4304184
Other Identifiers
ISSN
1756-8935
E-ISSN
1756-8935
DOI
10.1186/1756-8935-8-1
