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Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4304640

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

About this item

Full title

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2014-11, Vol.346 (6210), p.759-763

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The HIV-1 envelope (Env) mediates viral entry into host cells. To enable the direct imaging of conformational dynamics within Env, we introduced fluorophores into variable regions of the glycoprotein gp120 subunit and measured single-molecule fluorescence resonance energy transfer within the context of native trimers on the surface of HIV-1 virions...

Alternative Titles

Full title

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4304640

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4304640

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1254426

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