Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
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Publisher
United States: American Association for the Advancement of Science
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Language
English
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Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
The HIV-1 envelope (Env) mediates viral entry into host cells. To enable the direct imaging of conformational dynamics within Env, we introduced fluorophores into variable regions of the glycoprotein gp120 subunit and measured single-molecule fluorescence resonance energy transfer within the context of native trimers on the surface of HIV-1 virions...
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Full title
Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4304640
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4304640
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1254426