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Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4312207

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

About this item

Full title

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2015-01, Vol.517 (7536), p.621-625

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lineage-tracing experiments identify a rare, undifferentiated population of quiescent cells in the mouse distal lung that are activated through a Notch signalling pathway to repair the epithelium after bleomycin- or influenza-mediated injury; inappropriate Notch signalling may be a major contributor to failed regeneration within the lungs of patien...

Alternative Titles

Full title

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4312207

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4312207

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature14112

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