Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism
Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder in which leukemic cells display a reciprocal t(9:22) chromosomal translocation that results in the formation of the chimeric BCR-ABL oncoprotein, with a constitutive tyrosine kinase activity. Consequently, BCR-ABL causes increased proliferation, inhibition of apoptosis, and...
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Full title
Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4320527
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4320527
Other Identifiers
ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-015-0086-x
