PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission
PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission
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de Guglielmo, Giordano , Melis, Miriam , De Luca, Maria Antonietta , Kallupi, Marsida , Li, Hong Wu , Niswender, Kevin , Giordano, Antonio , Senzacqua, Martina , Somaini, Lorenzo , Cippitelli, Andrea , Gaitanaris, George , Demopulos, Gregory , Damadzic, Ruslan , Tapocik, Jenica , Heilig, Markus and Ciccocioppo, Roberto
Publisher
England: Nature Publishing Group
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English
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England: Nature Publishing Group
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PPARγ is one of the three isoforms identified for the peroxisome proliferator-activated receptors (PPARs) and is the receptor for the thiazolidinedione class of anti-diabetic medications including pioglitazone. PPARγ has been long studied for its role in adipogenesis and glucose metabolism, but the discovery of the localization in ventral tegmental...
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PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4330506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4330506
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ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/npp.2014.268
