Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcino...
Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib
About this item
Full title
Author / Creator
Wong, Andrea Li Ann , Lim, Joline Si Jing , Sinha, Arvind , Gopinathan, Anil , Lim, Robert , Tan, Chee-Seng , Soh, Thomas , Venkatesh, Sudhakar , Titin, Christina , Sapari, Nur Sabrina , Lee, Soo-Chin , Yong, Wei-Peng , Tan, David Shao Ping , Pang, Brendan , Wang, Ting-Ting , Zee, Ying-Kiat , Soong, Richie , Trnkova, Zuzana , Lathia, Chetan , Thiery, Jean-Paul , Wilhelm, Scott , Jeffers, Michael and Goh, Boon-Cher
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Regorafenib, a multi-kinase inhibitor, is used in the treatment of patients with metastatic colorectal cancer refractory to standard therapy. However, this benefit was limited to 1.4 months improvement in overall survival, with more than half of patients experiencing grade 3 to 4 adverse events. We aim to elucidate the pharmacodynamic effects of re...
Alternative Titles
Full title
Tumour pharmacodynamics and circulating cell free DNA in patients with refractory colorectal carcinoma treated with regorafenib
Authors, Artists and Contributors
Author / Creator
Lim, Joline Si Jing
Sinha, Arvind
Gopinathan, Anil
Lim, Robert
Tan, Chee-Seng
Soh, Thomas
Venkatesh, Sudhakar
Titin, Christina
Sapari, Nur Sabrina
Lee, Soo-Chin
Yong, Wei-Peng
Tan, David Shao Ping
Pang, Brendan
Wang, Ting-Ting
Zee, Ying-Kiat
Soong, Richie
Trnkova, Zuzana
Lathia, Chetan
Thiery, Jean-Paul
Wilhelm, Scott
Jeffers, Michael
Goh, Boon-Cher
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4332724
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4332724
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-015-0405-4
