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Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine

Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4333055

Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine

About this item

Full title

Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2015-03, Vol.11 (3), p.201-206

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The construction of ClpX hexamers containing variable numbers and configurations of wild-type and grip-defective pore loops supports a model of concurrent loop movement that ensures substrate unfolding and translocation.
Hexameric ATP-dependent proteases and protein remodeling machines use conserved loops that line the axial pore to apply force...

Alternative Titles

Full title

Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4333055

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4333055

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.1732

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