DNA damage response and prostate cancer: defects, regulation and therapeutic implications
DNA damage response and prostate cancer: defects, regulation and therapeutic implications
About this item
Full title
Author / Creator
Karanika, S , Karantanos, T , Li, L , Corn, P G and Thompson, T C
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
DNA damage response (DDR) includes the activation of numerous cellular activities that prevent duplication of DNA lesions and maintain genomic integrity, which is critical for the survival of normal and cancer cells. Specific genes involved in the DDR such as
BRCA1/2
and
P53
are mutated during prostate cancer progression, while various...
Alternative Titles
Full title
DNA damage response and prostate cancer: defects, regulation and therapeutic implications
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4333141
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4333141
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2014.238
