BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
About this item
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Author / Creator
Khaled, Walid T. , Choon Lee, Song , Stingl, John , Chen, Xiongfeng , Raza Ali, H. , Rueda, Oscar M. , Hadi, Fazal , Wang, Juexuan , Yu, Yong , Chin, Suet-Feung , Stratton, Mike , Futreal, Andy , Jenkins, Nancy A. , Aparicio, Sam , Copeland, Neal G. , Watson, Christine J. , Caldas, Carlos and Liu, Pentao
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Triple-negative breast cancer (TNBC) has poor prognostic outcome compared with other types of breast cancer. The molecular and cellular mechanisms underlying TNBC pathology are not fully understood. Here, we report that the transcription factor
BCL11A
is overexpressed in TNBC including basal-like breast cancer (BLBC) and that its genomic locu...
Alternative Titles
Full title
BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4338552
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4338552
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6987
